Muslim philosopher Avicenna released the first principles related to clinical trials around 1025 AD.
In 1920, Ronald A. Fisher and other English statisticians laid the groundwork of the techniques to be used in clinical trials, which led to the Nuremberg Code of 1947, a part of the “Doctors’ Trial”.
Next came the Declaration of Helsinki (1964) and the Tokyo Congress, most recently updated in 1975.
Tokyo Congress states, inter alia, that non-conforming tests are not allowed to be published.